Your friend is going to need to put down about 30-40% with almost any jumbo lender, especially a jumbo loan. ING has among the best rates, but they're guidelines are stringent and they only do ARMs
US Bank might be one to consider, but again, he'll need more down.
If he has a lot of assets, they're are some asset based lending programs that don't use the property as collateral but instead use the assets. That might be something to consider if he is over 5MM in some type of transferrable assets (stocks, real property/items...).
Jumbo's are a difficult proposition right now.